The cover illustrates the timeline of the introduction of DNA sequencing technologies and platforms. Next-generation sequencing is a high throughput sequencing technology, which has revolutionized both basic and clinical research of the human genetic disorders. This technology is also called massively parallel sequencing due to its ability to generate a huge amount of output data in a cost- and time-effective manner. To date, there have been several generations of sequencing technologies, which are different regarding sequencing principles, sequencing chemistries, and instrumentation.

 

To get more understanding about the topic, please see the full article "The applications of massive parallel sequencing (next-generation sequencing) in research and molecular diagnosis of human genetic diseases" in pages 30-43 of this issue.

Published: 2018-06-21

In vitro expression of enolase from Streptococcus suis serotype 2 and its antigenicity

Hoang Bach Nguyen, Thi Dang Khoa Nguyen, Gessica Tore, Van An Le, Alberto Alberti (Author)

24-29

Establishment of multiplex PCR for detection of genes related to Quinolone resistance

Ngo Tat Trung, Dao Thanh Quyen, Phan Quoc Hoan, Thirumalaisamy P.P. Velavan, Le Huu Song (Author)

51-55

DNA barcoding, an approach for molecular identification of Huyen-sam (Scrophularia L.) samples collected in Northern Vietnam

Manh Minh Bui, Anh Tuan Vu, Phuong Nhung Vu, Quang Cu Pham, Dang Ton Nguyen, Thi Thu Hue Huynh (Author)

56-64

BWTaligner: a genome short-read aligner

Lam Nguyen, Xuan Thi Trinh, Hien Trinh, Dang Hung Tran, Cuong Nguyen (Author)

73-77